Nature Communications (Dec 2020)
Single-cell atlas of the first intra-mammalian developmental stage of the human parasite Schistosoma mansoni
- Carmen Lidia Diaz Soria,
- Jayhun Lee,
- Tracy Chong,
- Avril Coghlan,
- Alan Tracey,
- Matthew D. Young,
- Tallulah Andrews,
- Christopher Hall,
- Bee Ling Ng,
- Kate Rawlinson,
- Stephen R. Doyle,
- Steven Leonard,
- Zhigang Lu,
- Hayley M. Bennett,
- Gabriel Rinaldi,
- Phillip A. Newmark,
- Matthew Berriman
Affiliations
- Carmen Lidia Diaz Soria
- Wellcome Sanger Institute, Wellcome Genome Campus
- Jayhun Lee
- Regenerative Biology, Morgridge Institute for Research
- Tracy Chong
- Regenerative Biology, Morgridge Institute for Research
- Avril Coghlan
- Wellcome Sanger Institute, Wellcome Genome Campus
- Alan Tracey
- Wellcome Sanger Institute, Wellcome Genome Campus
- Matthew D. Young
- Wellcome Sanger Institute, Wellcome Genome Campus
- Tallulah Andrews
- Wellcome Sanger Institute, Wellcome Genome Campus
- Christopher Hall
- Wellcome Sanger Institute, Wellcome Genome Campus
- Bee Ling Ng
- Wellcome Sanger Institute, Wellcome Genome Campus
- Kate Rawlinson
- Wellcome Sanger Institute, Wellcome Genome Campus
- Stephen R. Doyle
- Wellcome Sanger Institute, Wellcome Genome Campus
- Steven Leonard
- Wellcome Sanger Institute, Wellcome Genome Campus
- Zhigang Lu
- Wellcome Sanger Institute, Wellcome Genome Campus
- Hayley M. Bennett
- Wellcome Sanger Institute, Wellcome Genome Campus
- Gabriel Rinaldi
- Wellcome Sanger Institute, Wellcome Genome Campus
- Phillip A. Newmark
- Regenerative Biology, Morgridge Institute for Research
- Matthew Berriman
- Wellcome Sanger Institute, Wellcome Genome Campus
- DOI
- https://doi.org/10.1038/s41467-020-20092-5
- Journal volume & issue
-
Vol. 11,
no. 1
pp. 1 – 16
Abstract
Schistosomes undergo several develepmental stages during infection of humans. Here, the authors perform single-cell RNA sequencing on the earliest intra-mammalian stage of Schistosoma mansoni and generate a comprehensive cell-type atlas for this human parasite.
