Dendritic mitoflash as a putative signal for stabilizing long-term synaptic plasticity

Zhong-Xiao Fu; Xiao Tan; Huaqiang Fang; Pak-Ming Lau; Xianhua Wang; Heping Cheng; Guo-Qiang Bi

doi:10.1038/s41467-017-00043-3

Nature Communications (Jun 2017)

Dendritic mitoflash as a putative signal for stabilizing long-term synaptic plasticity

Zhong-Xiao Fu,
Xiao Tan,
Huaqiang Fang,
Pak-Ming Lau,
Xianhua Wang,
Heping Cheng,
Guo-Qiang Bi

Affiliations

Zhong-Xiao Fu: Hefei National Laboratory for Physical Sciences at the Microscale, University of Science and Technology of China
Xiao Tan: School of Life Sciences, University of Science and Technology of China
Huaqiang Fang: State Key Laboratory of Membrane Biology, Institute of Molecular Medicine, Peking-Tsinghua Center for Life Sciences, Peking University
Pak-Ming Lau: School of Life Sciences, University of Science and Technology of China
Xianhua Wang: State Key Laboratory of Membrane Biology, Institute of Molecular Medicine, Peking-Tsinghua Center for Life Sciences, Peking University
Heping Cheng: State Key Laboratory of Membrane Biology, Institute of Molecular Medicine, Peking-Tsinghua Center for Life Sciences, Peking University
Guo-Qiang Bi: Hefei National Laboratory for Physical Sciences at the Microscale, University of Science and Technology of China

DOI: https://doi.org/10.1038/s41467-017-00043-3
Journal volume & issue: Vol. 8, no. 1
pp. 1 – 12

Abstract

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Mitoflashes are dynamic events in mitochondria, associated with depolarization and release of reactive oxygen species, and have been associated with several cellular functions. The authors now show that in neurons, dendritic mitoflashes are involved in structural postsynaptic changes during LTP.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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