Thermal analysis of different shape nanoparticles on hyperthermia therapy on breast cancer in a porous medium: A fractional model
Dolat Khan,
Ata ur Rahman,
Poom Kumam,
Wiboonsak Watthayu,
Kanokwan Sitthithakerngkiet,
Ahmed M. Galal
Affiliations
Dolat Khan
Fixed Point Research Laboratory, Fixed Point Theory and Applications Research Group, Center of Excellence in Theoretical and Computational Science (TaCS-CoE), Faculty of Science, King Mongkut's University of Technology Thonburi (KMUTT), 126 Pracha Uthit Rd., Bang Mod, Thung Khru, Bangkok, 10140, Thailand; Center of Excellence in Theoretical and Computational Science (TaCS-CoE), Faculty of Science, King Mongkut's University of Technology Thonburi (KMUTT), 126 Pracha Uthit Rd., Bang Mod, Thung Khru, Bangkok, 10140, Thailand
Ata ur Rahman
Department of Mathematics, City University of Science & Information Technology, Peshawar, KPK, Pakistan
Poom Kumam
Fixed Point Research Laboratory, Fixed Point Theory and Applications Research Group, Center of Excellence in Theoretical and Computational Science (TaCS-CoE), Faculty of Science, King Mongkut's University of Technology Thonburi (KMUTT), 126 Pracha Uthit Rd., Bang Mod, Thung Khru, Bangkok, 10140, Thailand; Center of Excellence in Theoretical and Computational Science (TaCS-CoE), Faculty of Science, King Mongkut's University of Technology Thonburi (KMUTT), 126 Pracha Uthit Rd., Bang Mod, Thung Khru, Bangkok, 10140, Thailand; Department of Medical Research, China Medical University Hospital, China Medical University, Taichung, 40402, Taiwan; Corresponding author.
Wiboonsak Watthayu
Center of Excellence in Theoretical and Computational Science (TaCS-CoE), Faculty of Science, King Mongkut's University of Technology Thonburi (KMUTT), 126 Pracha Uthit Rd., Bang Mod, Thung Khru, Bangkok, 10140, Thailand
Kanokwan Sitthithakerngkiet
Intelligent and Nonlinear Dynamic Innovations Research Center, Department of Mathematics, Faculty of Applied Science, King Mongkut's University of Technology North Bangkok (KMUTNB), 1518, Wongsawang, Bangsue, Bangkok, 10800, Thailand
Ahmed M. Galal
Department of Mechanical Engineering, College of Engineering in Wadi Alddawasir, Prince Sattam Bin Abdulaziz University, Saudi Arabia; Production Engineering and Mechanical Design Department, Faculty of Engineering, Mansoura University, P. O. 35516, Mansoura, Egypt
Cancer is clearly a major cause of disease and fatality around the world, yet little is known about how it starts and spreads. In this study, a model in mathematical form of breast cancer guided by a system of (ODE’S) ordinary differential equations is studied in depth to examine the thermal effects of various shape nanoparticles on breast cancer hyperthermia therapy in the existence of a porous media with fractional derivative connection, when utilizing microwave radiative heating. The unsteady state is determined precisely using the Laplace transform approach to crop a more decisive examination of temperature dissemination of blood temperature inside the breast tissues. Durbin's and Zakian's techniques are used to find Laplace inversion. Mild temperature hyperthermia is used in the treatment, which promotes cell death by increasing cell nervousness to radiation therapy and flow of blood in tumor. In the graphical findings, we can witness the distinct behavior of hyperthermia therapy on tumor cells by applying various metabolic heat generation rates across various time intervals to attain the optimal therapeutic temperature point. Particularly, we used graphs to visualize the behavior of different Nanoparticles with different shaped during hypothermia therapy. In comparison to other nanoparticles and shapes, it demonstrates that gold nanoparticles with a platelet shape are the best option for improving heat transmission. Which assess of heat transfer up to 16.412%.
