Autoimmune polyglandular syndrome type 3: A case report of an unusual presentation and literature review

Abstract

Abstract Autoimmune polyglandular syndromes (APS) are rare disorders characterized by auto‐destruction of endocrine and non‐endocrine organs by organ‐specific antibody‐directed T‐lymphocytic infiltration. This case highlights a 29‐year‐old Caucasian man with vitiligo found to have significant neurological abnormalities in the setting of newly diagnosed pernicious anemia and thyroid autoimmune disease.

Keywords

• autoimmune polyglandular syndrome
• cobalamin deficiency
• subacute combined degeneration
• thyroid autoimmune disease
• pernicious anemia
• vitamin B12 deficiency