Nature Communications (Oct 2022)

The potential of Beta variant containing COVID booster vaccines for chasing Omicron in 2022

  • Saranya Sridhar,
  • Roman M. Chicz,
  • William Warren,
  • Jim Tartaglia,
  • Stephen Savarino,
  • Sanjay Gurunathan,
  • Jean-Francois Toussaint

DOI
https://doi.org/10.1038/s41467-022-33549-6
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 3

Abstract

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Currently approved COVID vaccines are designed using the spike antigen derived from the ancestral strain, but health authorities are recommending changes to the vaccine strain to combat emerging variants. The goal is to ensure that next generation vaccines can tackle multiple variants of concern including the most prevalent variant for the coming season. We here discuss recent preclinical and clinical data on COVID vaccine antigens that are potential candidates for an updated vaccine.