Gingival Swelling As Rare Presentation of Multiple Myeloma: A Case Report and Review Of Literature

Abstract

Multiple myeloma (MM) is a neoplastic disorder in which the fundamental abnormality is neoplastic proliferation of the plasma cells which infiltrate the bone marrow and often other body tissues. It is most commonly seen within the age range of 50-80 years. Men are affected more frequently. Bone pain is the cardinal clinical symptom. Plasma cell dyscrasias affect the jaws relatively infrequently and rarely this is the first sign of the disease. This article describes a rare case of a 45-year-old male who presented with bilateral non-tender gingival (jaw) swellings which were initially diagnosed as gingival or cystic dental pathology. The diagnosis of multiple myeloma was made histopathologically and supported by further investigations. The patient was treated by chemotherapy with good response clinically. The literature is reviewed with respect to the oral manifestations of MM.

Keywords

• Jaw swelling
• Mandibular lesion
• Dental Pathology
• Multiple myeloma
• Plasma cell dyscrasias