IEEE Journal of Translational Engineering in Health and Medicine (Jan 2014)

RFID Tag Helix Antenna Sensors for Wireless Drug Dosage Monitoring

  • Haiyu Huang,
  • Peisen Zhao,
  • Pai-Yen Chen,
  • Yong Ren,
  • Xuewu Liu,
  • Mauro Ferrari,
  • Ye Hu,
  • Deji Akinwande

DOI
https://doi.org/10.1109/JTEHM.2014.2309335
Journal volume & issue
Vol. 2
pp. 1 – 8

Abstract

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Miniaturized helix antennas are integrated with drug reservoirs to function as RFID wireless tag sensors for real-time drug dosage monitoring. The general design procedure of this type of biomedical antenna sensors is proposed based on electromagnetic theory and finite element simulation. A cost effective fabrication process is utilized to encapsulate the antenna sensor within a biocompatible package layer using PDMS material, and at the same time form a drug storage or drug delivery unit inside the sensor. The in vitro experiment on two prototypes of antenna sensor-drug reservoir assembly have shown the ability to monitor the drug dosage by tracking antenna resonant frequency shift from 2.4-2.5-GHz ISM band with realized sensitivity of 1.27 μ l/MHz for transdermal drug delivery monitoring and 2.76- μ l/MHz sensitivity for implanted drug delivery monitoring.

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