Frontiers in Psychiatry (Oct 2024)
Evaluating dysphagia in Alzheimer’s disease: the significance of age and medical comorbidities,a cross-sectional study from a tertiary psychiatric hospital in Guangzhou China
- Junrong Ye,
- Junrong Ye,
- Yuanxin Pan,
- Yuanxin Pan,
- Yuanxin Pan,
- Tingwei Zhou,
- Tingwei Zhou,
- Tingwei Zhou,
- Fei Liu,
- Fei Liu,
- Fei Liu,
- Yanheng Wei,
- Yanheng Wei,
- Jiao Chen,
- Jiao Chen,
- Jiao Chen,
- Wen Wang,
- Wen Wang,
- Wen Wang,
- Xueyu Zheng,
- Xueyu Zheng,
- Xueyu Zheng,
- Dingjie Liu,
- Dingjie Liu,
- Dingjie Liu,
- Shengwei Wu,
- Shengwei Wu,
- Zezhi Li,
- Zezhi Li,
- Jianxiong Guo,
- Jianxiong Guo,
- Aixiang Xiao,
- Aixiang Xiao
Affiliations
- Junrong Ye
- The Affiliated Brain Hospital, Guangzhou Medical University, Guangzhou, China
- Junrong Ye
- Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, Guangzhou Medical University, Guangzhou, China
- Yuanxin Pan
- The Affiliated Brain Hospital, Guangzhou Medical University, Guangzhou, China
- Yuanxin Pan
- Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, Guangzhou Medical University, Guangzhou, China
- Yuanxin Pan
- School of Nursing, Guangzhou Medical University, Guangzhou, China
- Tingwei Zhou
- The Affiliated Brain Hospital, Guangzhou Medical University, Guangzhou, China
- Tingwei Zhou
- Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, Guangzhou Medical University, Guangzhou, China
- Tingwei Zhou
- School of Nursing, Guangzhou Medical University, Guangzhou, China
- Fei Liu
- The Affiliated Brain Hospital, Guangzhou Medical University, Guangzhou, China
- Fei Liu
- Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, Guangzhou Medical University, Guangzhou, China
- Fei Liu
- Kiang Wu Nursing College of Macau, Macao, Macao SAR, China
- Yanheng Wei
- The Affiliated Brain Hospital, Guangzhou Medical University, Guangzhou, China
- Yanheng Wei
- Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, Guangzhou Medical University, Guangzhou, China
- Jiao Chen
- The Affiliated Brain Hospital, Guangzhou Medical University, Guangzhou, China
- Jiao Chen
- Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, Guangzhou Medical University, Guangzhou, China
- Jiao Chen
- School of Nursing, Guangzhou Medical University, Guangzhou, China
- Wen Wang
- The Affiliated Brain Hospital, Guangzhou Medical University, Guangzhou, China
- Wen Wang
- Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, Guangzhou Medical University, Guangzhou, China
- Wen Wang
- School of Nursing, Guangzhou Medical University, Guangzhou, China
- Xueyu Zheng
- The Affiliated Brain Hospital, Guangzhou Medical University, Guangzhou, China
- Xueyu Zheng
- Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, Guangzhou Medical University, Guangzhou, China
- Xueyu Zheng
- School of Nursing, Guangzhou Medical University, Guangzhou, China
- Dingjie Liu
- The Affiliated Brain Hospital, Guangzhou Medical University, Guangzhou, China
- Dingjie Liu
- Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, Guangzhou Medical University, Guangzhou, China
- Dingjie Liu
- School of Nursing, Guangzhou Medical University, Guangzhou, China
- Shengwei Wu
- The Affiliated Brain Hospital, Guangzhou Medical University, Guangzhou, China
- Shengwei Wu
- Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, Guangzhou Medical University, Guangzhou, China
- Zezhi Li
- The Affiliated Brain Hospital, Guangzhou Medical University, Guangzhou, China
- Zezhi Li
- Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, Guangzhou Medical University, Guangzhou, China
- Jianxiong Guo
- The Affiliated Brain Hospital, Guangzhou Medical University, Guangzhou, China
- Jianxiong Guo
- Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, Guangzhou Medical University, Guangzhou, China
- Aixiang Xiao
- The Affiliated Brain Hospital, Guangzhou Medical University, Guangzhou, China
- Aixiang Xiao
- Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, Guangzhou Medical University, Guangzhou, China
- DOI
- https://doi.org/10.3389/fpsyt.2024.1482951
- Journal volume & issue
-
Vol. 15
Abstract
ObjectiveTo investigate the influencing factors of dysphagia in Alzheimer’s disease (AD) patients.MethodsThe study evaluated the demographic characteristics, nutritional status, social functioning, and swallowing dysfunction of 109 hospitalized AD patients.ResultsThe sample include 65.1% of female patients, mainly concentrate in >70 years old (72.5%). The illness duration is mainly 0~5 years (62.4%). After adjusting for confounding factors such as gender, poor lifestyle habits, illness duration, marital status, route to admission, concomitant medical illness, nutritional status, and social functioning, we find that the swallowing function in patients with AD is related to route to admission and concomitant medical illness (mainly includes: circulatory disease and respiratory disease). Age ≥90 years old and more concomitant medical illness contribute to a lower swallowing dysfunction score in patients with AD (P<0.05).ConclusionAge and concomitant medical illness are the important influencing factors in swallowing dysfunction in patients with AD. Therefore, we believe that future research should focus on the treatment and care of patients with medical conditions in order to enhance the swallowing function in patients with AD.
Keywords
- Alzheimer disease patients
- swallowing function
- influencing factors
- cross-sectional study
- elderly patients
