Nature Communications (Jun 2019)

CAPRI enables comparison of evolutionarily conserved RNA interacting regions

  • Amol Panhale,
  • Florian M. Richter,
  • Fidel Ramírez,
  • Maria Shvedunova,
  • Thomas Manke,
  • Gerhard Mittler,
  • Asifa Akhtar

DOI
https://doi.org/10.1038/s41467-019-10585-3
Journal volume & issue
Vol. 10, no. 1
pp. 1 – 22

Abstract

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Comprehensive characterisation of RNA-protein interactions requires different levels of resolution. Here, the authors present an integrated mass spectrometry-based approach that allows them to define the Drosophila RNA-protein interactome from the level of multisubunit complexes down to the RNA-binding amino acid.