Kikuchi-Fujimoto disease: A study of Four cases

Abstract

Kikuchi-Fujimoto disease (KFD) manifests in most cases as unilateral cervical lymphadenomegaly with or without accompanying fever. The disease is rare and mainly affects young women and has a self-limited course. KFD should be included in the differential diagnosis of suspected cases of viral infections, tuberculosis, reactive lymphadenitis, systemic lupus erythematosus and metastatic diseases. It can be histologically confused with lymphoma. The disease is benign and selflimiting and an excisional biopsy of an affected lymph node is often necessary for diagnosis. There is no specific therapy. This study reports four cases of female patients with KFD who were attended at Yashoda hospital, Malakpet. A review of the literature was carried out with a systematic search on this topic with the aim of informing physicians about this entity that is manifested by cervical masses and fever. Fourth case was interesting because of its association with autoimmune disease (SLE-systemic lupus erythematosus

Keywords

• kikuchi disease
• histiocytic necrotizing lymphadenitis
• lymphatic diseases
• neck
• lymph nodes