mSphere (Aug 2021)

Human Basigin (CD147) Does Not Directly Interact with SARS-CoV-2 Spike Glycoprotein

  • Robert J. Ragotte,
  • David Pulido,
  • Francesca R. Donnellan,
  • Michelle L. Hill,
  • Giacomo Gorini,
  • Hannah Davies,
  • Juliane Brun,
  • Kirsty McHugh,
  • Lloyd D. W. King,
  • Katherine Skinner,
  • Kazutoyo Miura,
  • Carole A. Long,
  • Nicole Zitzmann,
  • Simon J. Draper

DOI
https://doi.org/10.1128/mSphere.00647-21
Journal volume & issue
Vol. 6, no. 4

Abstract

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Reducing the mortality and morbidity associated with COVID-19 remains a global health priority. Vaccines have proven highly effective at preventing infection and hospitalization, but efforts must continue to improve treatment options for those who still become seriously ill.