Radiology Case Reports (May 2024)

Neurosarcoidosis with enlargement of the dorsal root ganglia: A case report

  • Sakie Namba,
  • Hajime Yokota,
  • Hiroki Mukai,
  • Jun Hashiba,
  • Naoki Kogayo,
  • Tatsushi Nakao,
  • Atsuhiko Sugiyama,
  • Etsuko Ogaya,
  • Yuya Aotsuka,
  • Satoshi Kuwabara,
  • Takashi Uno

Journal volume & issue
Vol. 19, no. 5
pp. 1718 – 1721

Abstract

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We report the case of a woman in her 40s who presented with sensory disturbances in all 4 limbs and left facial palsy. MRI revealed asymmetric enlargement of the dorsal root ganglia, which was enhanced by gadolinium—a chest CT scan identified enlarged supraclavicular, mediastinal, and hilar lymph nodes. A biopsy of a hilar lymph node showed noncaseating epithelioid granulomas, confirming a sarcoidosis diagnosis. Prednisolone treatment led to symptomatic improvements. In sarcoidosis of the peripheral nervous system, there might be observable enlargement of the dorsal root ganglion alongside enhanced gadolinium contrast. Obtaining a biopsy from the dorsal root ganglion poses challenges, and radiologists should be mindful of this specific imaging characteristic.

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