Use of octreotide for prevention of pancreatic leak after pancreatoduodenectomy: study progress

Abstract

The pancreatic leak after pancreaticoduodenectomy was one of the main causes of postoperative death, the rate of which remained high. Octreotide, an octapeptide somatostatin analogue, has been used in the prevention and treatment of postoperative pancreatic leak since the 1 990 s. However, octreotide availability was controversial until now. The study on the prevention of pancreatic leak after pancreaticoduodenectomy using octreotide was reviewed in this article.

Keywords

• |octreotide|postoperative pancreatic leak|pancreaticoduodenectomy