Derangement in renal & liver function in geriatric population with anaemia - A cross sectional study

Abstract

Background: Across the globe several studies have shown different etiologies of anemia in old age, likely to belief anemia is not a consequence of senescence. Objectives: Primary objective was to estimate prevalence of Renal & Hepatic impairment and secondary objective was to determine any association between Renal or Hepatic impairment with variable degrees of anemia. Methods: This was a cross-sectional descriptive observational study. 278 samples were included of above 60yrs old suffering from Anemia. Prevalence of kidney & liver disease was calculated in percentages. Association between kidney and liver disease with severity of anemia was measured by prevalence ratio. Result: The prevalence of derangement in renal and hepatic function were found 14.1% (95%CI: 10.5,18.9) and 6.1% (95%CI:3.3,8.9) respectively. Prevalence ratio of moderate to severe anemia with impaired renal function in comparison to healthy kidney function is 1.6(95%CI: 1.2,2.2) and this same ratio with deranged hepatic function is 1.7(95%CI:1.1,2.6). Conclusion: The magnitude of kidney and liver disease in our study population was found to be above 10% and 5% respectively, and also have an association with severity of anemia. Hence anemia should always be looked for & renal & hepatic functions need to be monitored in the geriatric population.

Keywords

• impaired renal function
• deranged hepatic function
• geriatric
• anemia