فیزیولوژی ورزش و فعالیت بدنی (Apr 2010)

Effects of aerobic training on soluble intercellular adhesion molecule-1 (sICAM-1) and lipid profile in overweight elderly women

  • اکبر اعظمیان جزی,
  • محمد فرامرزی,
  • فهیمه صفاری فارسانی

DOI
https://doi.org/10.48308/joeppa.2010.98572
Journal volume & issue
Vol. 3, no. 1

Abstract

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Effects of aerobic training on soluble intercellular adhesion molecule-1 (sICAM-1)and lipid profile in overweight elderly womenPurpose: Occurrences of cardiovascular diseases are usually predicted via lipid profile measuring,however, cardiovascular diseases are also observed in people with natural lipid profile. Hence, theinvestigators try to find more sensitive inflammatory markers such as soluble intercellular adhesionmolecule-1 (sICAM-1). Therefore, the present study aimed to investigate the effects of 8 week aerobictraining on sICAM-1 and lipid profile in Iranian overweight elderly women. Methods: In this semiexperimentalstudy, 40 overweight elderly women (72±7 years) who had no regular physical activitywere non-randoinly selected as the subjects, randomly divided into experimental (n = 20) and controlgroups (n = 20). Fasting blood samples were taken before and after 8 weeks of aerobic training. Aerobictraining was performed at an intensity corresponding to 60% of the subjects' maximal heart rate for 3d/wk and for 8 weeks. Kolmogrov Smirnov test was shown normal distribution of data, so paired t-testwas used to determine the differences between before and after training data in each group, andindependent t-test was used to compare data in training and control groups. Statistical significance wasset at P < 0.05. Results: LDL-C, TC, TG, sICAM-1 levels and BMI significantly decreased and HDL-Cincreased non-significantly in the experimental group after 8 weeks of aerobic training. There was nosignificant changes observed between the groups in HDL-C and TC, but LDL-C, TG, sICAM-1 andBMI changed significantly. Conclusion: Aerobic training may be having an important role in theprevention and control of cardiovascular diseases in elderly women by decreasing sICAM-1, LDL-C,TG and TC. Also, due to this fact that sICAM-1 is more sensitive than lipid profile, it is reasonable tomeasure it in accurate evaluation for incidence of cardiovascular diseases.

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