The latest treatment of colorectal cancer - a review paper

Abstract

The review article discusses the latest therapeutic approaches in the treatment of colorectal cancer (CRC), with a particular focus on metastatic disease. Despite advancements in standard treatments such as surgery, chemotherapy, and targeted therapies, the prognosis for patients with metastatic CRC remains poor, with five-year survival rates still low. The article examines the potential of immunotherapy, including PD-1 inhibitors like dostarlimab, which have shown promising results in treating selected patient groups. Additionally, the role of the ketogenic diet and probiotics as supportive strategies in CRC treatment is discussed, highlighting their potential to influence cancer metabolism and improve therapeutic outcomes. The article also addresses the development of nanotechnology-based therapies, such as PEGylated PLGA nanoparticles and sphingomyelin nanosystems, which may enhance drug delivery precision, thereby improving treatment efficacy and minimizing side effects. The conclusion emphasizes the need for further research into these innovative therapies and their integration with existing treatment protocols to improve survival and quality of life for CRC patients.

Keywords

• colorectal cancer
• immunotherapy
• oncology
• crc
• latest treatment of colorectal cancer
• nutrition in colorectal cancer