CLINICAL AND FUNCTIONAL RELATIONSHIPS IN CHRONIC RENAL DISEASES IN CHILDREN

Abstract

Among pediatricians — nephrologists there is no unified point of view on the appropriateness of the use of the term «Chronic kidney disease» (CKD) and its classification worked out by an international group of experts’ of Kidney Disease Outcomes Quality Initiative (K/DOQI) based on studies in adults. The aim of the study is to determine the correlation between the frequency of important symptoms (arterial hypertension (AG), anemia) of CKD with its stages in children. The study involved 295 patients with CKD: 213 children with glomerulopathy, 82 children — with nonglomerular diseases. We found positive correlations between the frequency of AG and anemia with CKD stages. The most significant differences were found between early and late stages of CKD. The nature of the kidney damage produced less impact on the frequency of these symptoms. Given the need for continuity professionals and international harmonization of terminology, it is appropriate to continue the search for markers of cardiovascular disease in the early stages of CKD, as well as to set target values of blood pressure and hemoglobin, depending on the stage of CKD in children.

Keywords

• chronic kidney disease
• arterial hypertension
• anemia
• children