Journal of Medical Case Reports (Jul 2017)

Primary solitary plasmacytoma of the liver – successful treatment with fractionated stereotactic radiotherapy (Cyberknife®): a case report

  • Thomas Chalopin,
  • Isabelle Barillot,
  • Jean-Paul Biny,
  • Flavie Arbion,
  • Marie Besson,
  • Maria Santiago-Ribeiro,
  • Eric Piver,
  • Olivier Herault,
  • Emmanuel Gyan,
  • Lotfi Benboubker

DOI
https://doi.org/10.1186/s13256-017-1358-4
Journal volume & issue
Vol. 11, no. 1
pp. 1 – 4

Abstract

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Abstract Background Solitary plasmacytoma of the liver is a very rare and aggressive form of plasma cell dyscrasia. To the best of our knowledge, very few cases have been reported without systemic disease. We reported a rare case of hepatic solitary plasmacytoma that successfully responded to fractionated stereotactic radiotherapy. Case presentation A 64-year-old white French man had monoclonal gammopathy of the immune globulin G lambda type; he developed a cholestasis and cytolysis with the discovery of a subscapular nodule. A biopsy showed plasma cells and, for several reasons, the decision was made to use the fractionated stereotactic radiotherapy strategy. After 20 months, he is asymptomatic and the immune globulin G component has completely disappeared. Conclusion We suggest considering Cyberknife® radiosurgery as an option for the treatment of hepatic solitary plasmacytoma.

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