In situ transcriptomic analysis of spermatocytes in non-obstructive azoospermia reveals senescence-like states in arrested spermatocytes

• Zhongqin Wu,
• Xiaolong Wu,
• Zeqian Xu,
• Yixin Liu,
• Ziyi Zhu,
• Xinhui Li,
• Daniel M. Czajkowsky,
• Fei Sun,
• Yan Guo,
• Zhifeng Shao

Affiliations

Zhongqin Wu

State Key Laboratory of Systems Medicine for Cancer, School of Biomedical Engineering and Bio-ID Center, Shanghai Jiao Tong University, Shanghai 200240, China

Xiaolong Wu

Department of Urology and Andrology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310016, China

Zeqian Xu

State Key Laboratory of Systems Medicine for Cancer, School of Biomedical Engineering and Bio-ID Center, Shanghai Jiao Tong University, Shanghai 200240, China

Yixin Liu

State Key Laboratory of Systems Medicine for Cancer, School of Biomedical Engineering and Bio-ID Center, Shanghai Jiao Tong University, Shanghai 200240, China

Ziyi Zhu

State Key Laboratory of Systems Medicine for Cancer, School of Biomedical Engineering and Bio-ID Center, Shanghai Jiao Tong University, Shanghai 200240, China

Xinhui Li

State Key Laboratory of Systems Medicine for Cancer, School of Biomedical Engineering and Bio-ID Center, Shanghai Jiao Tong University, Shanghai 200240, China

Daniel M. Czajkowsky

State Key Laboratory of Systems Medicine for Cancer, School of Biomedical Engineering and Bio-ID Center, Shanghai Jiao Tong University, Shanghai 200240, China

Fei Sun

Department of Urology and Andrology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310016, China; Corresponding author.

Yan Guo

State Key Laboratory of Systems Medicine for Cancer, School of Biomedical Engineering and Bio-ID Center, Shanghai Jiao Tong University, Shanghai 200240, China; Corresponding author.

Zhifeng Shao

State Key Laboratory of Systems Medicine for Cancer, School of Biomedical Engineering and Bio-ID Center, Shanghai Jiao Tong University, Shanghai 200240, China