Prevalence of Non-Viral Bloodborne Pathogens Among Healthy Blood Donors in Western Mexico: Problems and Failures of Public Health Policy
José de Jesús Guerrero-García,
Alejandra Flores-González,
Alma Marina Sánchez-Sánchez,
Rafael Magaña-Duarte,
Mario Alberto Mireles-Ramírez,
Pablo Cesar Ortiz-Lazareno,
Erick Sierra Díaz,
Daniel Ortuño-Sahagún
Affiliations
José de Jesús Guerrero-García
Banco de Sangre Central, Unidad Médica de Alta Especialidad (UMAE), Hospital de Especialidades (HE), Centro Médico Nacional de Occidente (CMNO), Instituto Mexicano del Seguro Social (IMSS), Guadalajara 44340, Mexico
Alejandra Flores-González
Departamento de Farmacobiología, Centro Universitario de Ciencias Exactas e Ingenierías (CUCEI), Universidad de Guadalajara, Guadalajara 44340, Mexico
Alma Marina Sánchez-Sánchez
Laboratorio de Neuroinmunobiología Molecular, Instituto de Investigación en Ciencias Biomédicas (IICB), Centro Universitario de Ciencias de la Salud (CUCS), Universidad de Guadalajara, Guadalajara 44340, Mexico
Rafael Magaña-Duarte
Banco de Sangre Central, Unidad Médica de Alta Especialidad (UMAE), Hospital de Especialidades (HE), Centro Médico Nacional de Occidente (CMNO), Instituto Mexicano del Seguro Social (IMSS), Guadalajara 44340, Mexico
Mario Alberto Mireles-Ramírez
Dirección de Investigación y Educación en Salud, Unidad Médica de Alta Especialidad (UMAE), Hospital de Especialidades (HE), Centro Médico Nacional de Occidente (CMNO), Instituto Mexicano del Seguro Social (IMSS), Guadalajara 44340, Mexico
Pablo Cesar Ortiz-Lazareno
División de Inmunología, Centro de Investigación Biomédica de Occidente (CIBO), Instituto Mexicano del Seguro Social (IMSS), Guadalajara 44340, Mexico
Erick Sierra Díaz
División de Epidemiología, Unidad Médica de Alta Especialidad (UMAE), Hospital de Especialidades (HE), Centro Médico Nacional de Occidente (CMNO), Instituto Mexicano del Seguro Social (IMSS), Guadalajara 44340, Mexico
Daniel Ortuño-Sahagún
Laboratorio de Neuroinmunobiología Molecular, Instituto de Investigación en Ciencias Biomédicas (IICB), Centro Universitario de Ciencias de la Salud (CUCS), Universidad de Guadalajara, Guadalajara 44340, Mexico
Background and Objectives: Non-viral bloodborne diseases are a group of infections that are a public health problem worldwide. The incidence of diseases such as brucellosis and syphilis is increasing in the Americas and Europe. Chagas disease is an endemic problem in Latin America, the United States and Europe. This study aims to determine the prevalence of non-viral bloodborne diseases in blood donors and to discuss some issues related to federal regulations for the control and prevention of these infectious diseases in Mexico. Material and methods: A cross-sectional study was conducted in the Western National Medical Center Blood Bank, including 228,328 blood donors (2018–2023). Frequencies, percentages, means, standard deviation and confidence intervals (CI) were calculated for demographic data. Prevalences were expressed as rates per 100,000 with 95% CI. Results: Of 3949 seroreactive or undetermined blood donors at the first screening, a total of 682 (0.299%) completed their follow-up test and were positive for Treponema pallidum (478), Trypanosoma cruzi (83), or Brucella spp. (121). The overall prevalence for non-viral bloodborne diseases was 299 per 100,000 blood donors. The prevalence for syphilis, Chagas disease, and Brucella was 209, 36, and 53 per 100,000 respectively. Conclusion: Federal regulations should be reviewed to formulate specific public health policies focused on controlling and preventing nonviral bloodborne diseases.
