Biologically active compounds of bioresidues of Crocus Sativus flower

Abstract

Secondary metabolites present in Crocus sativus L. petals (saffron) grown in Uzbekistan, were studied for the first time. According to the results of phytochemical studies, it was observed that biowaste contains a large amount of biologically active flavonoids, anthocyanins, carotenoids, phenolic carbonic acids, terpenoids, saponins, micro- and macroelements, exchangeable and non-exchangeable amino acids as well as unsaturated fatty acids necessary for the human body. Pharmacological studies have shown that total flavonoids isolated from Crocus sativus petals exhibit antihypoxic activity (observed under conditions of acute normobaric and hemic hypoxia) and antioxidant properties obtained in in vivo experiments (determined by the accumulation of malondialdehyde). It has been established that its antihypoxic and antioxidant activity is higher than that of the rutin and luteolin.