ABCD: Arquivos Brasileiros de Cirurgia Digestiva (Sep 2024)

RATIO OF METASTATIC LYMPH NODES VS. RESECTED LYMPH NODES (N-RATIO) HAS PROGNOSTIC IMPLICATIONS IN GASTRIC CANCER

  • Breno Cordeiro PORTO,
  • Marina Alessandra PEREIRA,
  • Marcus Fernando Kodama Pertille RAMOS,
  • André Roncon DIAS,
  • Fábio Pinatel LOPASSO,
  • Luiz Augusto Carneiro D’ALBUQUERQUE,
  • Ulysses RIBEIRO JUNIOR

DOI
https://doi.org/10.1590/0102-6720202400031e1824
Journal volume & issue
Vol. 37

Abstract

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ABSTRACT BACKGROUND: Lymph node status is vital for gastric cancer (GC) prognosis, but the conventional pN stage may be limited by variations in lymphadenectomy and stage migration. The N-Ratio, which assesses the ratio of metastatic to resected lymph nodes, emerges as a promising prognostic tool. AIMS: To assess N-Ratios prognostic value in GC, particularly in patients with 0.05) and N-Ratio 1 (66.2 vs. 50%, p=0.504, p>0.05) groups. The DFS of N-Ratio-0 cases with <25 lymph nodes was similar to N-Ratio 1 cases. CONCLUSIONS: N-Ratio influenced survival in GC patients, especially in advanced lymph node disease (N-Ratio 3). Considering that N-Ratio does not impact pN0 cases, individualized prognosis assessment is essential for patients with <25 resected lymph nodes.

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