Non-Invasive MRI of Blood–Cerebrospinal Fluid Barrier Function

P. G. Evans; M. Sokolska; A. Alves; I. F. Harrison; Y. Ohene; P. Nahavandi; O. Ismail; E. Miranda; M. F. Lythgoe; D. L. Thomas; J. A. Wells

doi:10.1038/s41467-020-16002-4

Nature Communications (Apr 2020)

Non-Invasive MRI of Blood–Cerebrospinal Fluid Barrier Function

P. G. Evans,
M. Sokolska,
A. Alves,
I. F. Harrison,
Y. Ohene,
P. Nahavandi,
O. Ismail,
E. Miranda,
M. F. Lythgoe,
D. L. Thomas,
J. A. Wells

Affiliations

P. G. Evans: UCL Centre for Advanced Biomedical Imaging, Division of Medicine, University College London
M. Sokolska: Medical Physics and Biomedical Engineering, University College London Hospitals NHS Foundation Trust
A. Alves: Pathology Core Facility, University College London Cancer Institute
I. F. Harrison: UCL Centre for Advanced Biomedical Imaging, Division of Medicine, University College London
Y. Ohene: UCL Centre for Advanced Biomedical Imaging, Division of Medicine, University College London
P. Nahavandi: UCL Centre for Advanced Biomedical Imaging, Division of Medicine, University College London
O. Ismail: UCL Centre for Advanced Biomedical Imaging, Division of Medicine, University College London
E. Miranda: Pathology Core Facility, University College London Cancer Institute
M. F. Lythgoe: UCL Centre for Advanced Biomedical Imaging, Division of Medicine, University College London
D. L. Thomas: Neuroradiological Academic Unit, Department of Brain Repair and Rehabilitation, UCL Queen Square Institute of Neurology
J. A. Wells: UCL Centre for Advanced Biomedical Imaging, Division of Medicine, University College London

DOI: https://doi.org/10.1038/s41467-020-16002-4
Journal volume & issue: Vol. 11, no. 1
pp. 1 – 11

Abstract

Read online

The blood–cerebrospinal fluid barrier (BCSFB) is an important interface for brain homeostasis. Here the authors describe a non-invasive MRI technique for the quantitative assessment of BCSFB function.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

About the journal