Biosensors (May 2021)

Simultaneous Imaging of Bio- and Non-Conductive Targets by Combining Frequency and Time Difference Imaging Methods in Electrical Impedance Tomography

  • Xue Bai,
  • Dun Liu,
  • Jinzhao Wei,
  • Xu Bai,
  • Shijie Sun,
  • Wenbin Tian

DOI
https://doi.org/10.3390/bios11060176
Journal volume & issue
Vol. 11, no. 6
p. 176

Abstract

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As a promising medical imaging modality, electrical impedance tomography (EIT) can image the electrical properties within a region of interest using electrical measurements applied at electrodes on the region boundary. This paper proposes to combine frequency and time difference imaging methods in EIT to simultaneously image bio- and non-conductive targets, where the image fusion is accomplished by applying a wavelet-based technique. To enable image fusion, both time and frequency difference imaging methods are investigated regarding the reconstruction of bio- or non-conductive inclusions in the target region at varied excitation frequencies, indicating that none of those two methods can tackle with the scenarios where both bio- and non-conductive inclusions exist. This dilemma can be resolved by fusing the time difference (td) and appropriate frequency difference (fd) EIT images since they are complementary to each other. Through simulation and in vitro experiment, it is demonstrated that the proposed fusion method can reasonably reconstruct both the bio- and non-conductive inclusions within the lung models established to simulate the ventilation process, which is expected to be beneficial for the diagnosis of lung-tissue related diseases by EIT.

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