Cardiovascular Ultrasound (Apr 2007)

Takotsubo cardiomyopathy in a Caucasian Italian woman: Case report

  • Castellani Debora,
  • Carrera Arcangelo,
  • Aitiani Paolo,
  • Lunghetti Stefano,
  • Maggi Marianna,
  • Casucci Francesca,
  • Maffei Silvia,
  • Zacà Valerio,
  • Lisi Matteo,
  • Favilli Roberto,
  • Pierli Carlo,
  • Mondillo Sergio

DOI
https://doi.org/10.1186/1476-7120-5-18
Journal volume & issue
Vol. 5, no. 1
p. 18

Abstract

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Abstract Background Takotsubo cardiomyopathy is an acute cardiac syndrome characterized by transient LV regional wall motion abnormalities (with peculiar apical ballooning appearance), chest pain or dyspnea, ST-segment elevation and minor elevations of cardiac enzyme levels Case presentation A 68-year-old woman was admitted to the Emergency Department because of sudden onset chest pain occurred while transferring her daughter, who had earlier suffered a major seizure, to the hospital. The EKG showed sinus tachycardia with ST-segment elevation in leads V2–V3 and ST-segment depression in leads V5–V6, she was, thus, referred for emergency coronary angiography. A pre-procedural transthoracic echocardiogram revealed regional systolic dysfunction of the LV walls with hypokinesis of the mid-apical segments and hyperkinesis of the basal segments. Coronary angiography showed patent epicardial coronary arteries; LV angiography demonstrated the characteristic morphology of apical ballooning with hyperkinesis of the basal segments and hypokinesis of the mid-apical segments. The post-procedural course was uneventful; on day 5 after admission the echocardiogram revealed full recovery of apical and mid-ventricular regional wall-motion abnormalities. Conclusion Takotsubo cardiomyopathy is a relatively rare, unique entity that has only recently been widely appreciated. Acute stress has been indicated as a common trigger for the transient LV apical ballooning syndrome, especially in postmenopausal women. The present report is a typical example of stress-induced takotsubo cardiomyopathy in a Caucasian Italian postmenopausal woman.