Development of a UHPLC-MS/MS method for the determination of quercetin in milk and its application to a pharmacokinetic study

Abstract

Introduction: Quercetin is a polyphenolic flavonoid which has been used in traditional Chinese medicine as a natural therapeutic agent with a broad spectrum of activities (antioxidant, anticancer, neuroprotective, anti-inflammatory, antiviral and antibacterial). The aim of this study was to develop and validate a rapid and simple ultra-high-performance liquid chromatography with tandem mass spectrometry (UHPLC-MS/MS) method for the determination of quercetin in milk.

Keywords

• quercetin
• uhplc-ms/ms
• milk
• pharmacokinetics