Cytological and Histopathological Correlation of Patterns of Breast Lesions in Women above 18 Years at a Tertiary Care Government Teaching Hospital in Jaipur

Abstract

Introduction: Breast lesions commonly present as a breast lump. The most accepted protocol followed for the diagnosis of a breast lump is a triple assessment which includes clinical assessment, radiological imaging, and pathological diagnosis. Fine needle aspiration cytology (FNAC) and histopathological biopsy are techniques for pathological diagnosis. FNAC is an invasive technique with minimum trauma to patients while histopathology requires surgical excision of lesions. Methodology: A total of 100 female patients attending the surgical outpatient department with clinically palpable breast lump and age less than 18 years were enrolled in the study. Details of case history and clinical examination were recorded. Fine needle aspiration with 22-23 gauze needle was carried out. Cytomorphological observations were recorded and cyto-diagnosis was given. After surgical excision of lump, histo-pathological diagnosis were given after routine tissue processing. Cytopathological findings were then correlated with histopathological findings. Results: In the study, the sensitivity, specificity, positive predictive value, and negative predictive value of cytology as compared with histopathology were 92.30%, 97.18%, 92.30%, and 97.18%, respectively. Conclusion: FNAC can be relied upon for early diagnosis, its diagnostic efficacy is further enhanced when combined with clinical features and radiology.

Keywords

• Fibroadenoma, Fine needle aspiration cytology, Lobular carcinoma.