Determination of clinical state of hepatitis B virus infection of patients in Basra governorate

Abstract

Hepatitis B virus is a hepatotropic virus that causes acute and chronic hepatitis, liver cirrhosis and hepatocellular carcinoma; it is responsible for more than one million deaths annually worldwide despite hepatitis B vaccination. So, the aim of the present study was to detect the total markers of HBV (HBsAg, HBsAb, HBeAg, HBeAb, Total anti-HBc and IgM anti-HBc) .A total of 126 cases with hepatitis B were recruited from different medical centers in Basra. Serological tests were preformed for all cases using ELISA tests. 126 patients were divided into 8 studied groups including: Incubation, Active acute, Acute, Active chronic, chronic, Inactive HBsAg Carrier, HBsAg-negative patients and liver cancer. We conclude that the vast majority of patients were Inactive HBsAg Carrier (54.76 %) fallowed by acute hepatitis (16.67 %) and HBsAg-negative patients (7.14 %).