Mayer-Rokitansky-Kuster-Hauser syndrome: a review

Abstract

Laura Londra, Farah S Chuong, Lisa KolpDivision of Reproductive Endocrinology and Infertility, Department of Gynecology and Obstetrics, Johns Hopkins University, Baltimore, MD, USAAbstract: The congenital aplasia or severe hypoplasia of mullerian structures is infrequent. However, the features of normal female endocrine function paired with the absence of a functional uterus and vagina makes it a fascinating entity. The diagnosis and work-up in these patients has become very efficient, thanks to the use of imaging, and there are multiple successful procedures for the creation of a neovagina. In recent years, infertility treatment options through in vitro fertilization have also become available as part of the long-term care of these patients.Keywords: vaginal agenesis, neovagina, MRKH, mullerian agenesis