Pollen allergy and pollen sensitization: a new look at an old subject

Abstract

Relevance. Allergic diseases associated with hypersensitivity to pollen allergens (pollinosis) are an urgent medical and socio-economic problem due to widespread increase in prevalence, a variety of clinical manifestations and a negative impact on the quality of life. Understanding the mechanisms underlying the initiation of sensitization to plant-derived airborne allergens can become the basis for development innovative strategies for the treatment and prevention of hay fever. The aim of the review is to analyze and systematize the currently available data on the mechanisms of the initiation of pollen sensitization and the realization of allergy to pollen allergens. The purpose of this article: to systematize the information available today on the influence of the composition of the intestinal microflora on the immunopathogenesis of atopic dermatitis.

Keywords

• allergy
• pollen
• sensitization
• allergens
• pollutants
• adjuvants