Antibodies to Modulate Surface Receptor Systems Are Often Bivalent and Must Compete in a Two‐Dimensional Cell Contact Region

• Brian J. Schmidt,
• Christine Bee,
• Minhua Han,
• Yawu Jing,
• Yougan Cheng,
• Daniel J. Tenney,
• Tarek A. Leil

Affiliations

Brian J. Schmidt

Quantitative Clinical Pharmacology Bristol‐Myers Squibb Princeton New Jersey USA

Christine Bee

Biologics Discovery California Bristol‐Myers Squibb Redwood City California USA

Minhua Han

Biologics Discovery California Bristol‐Myers Squibb Redwood City California USA

Yawu Jing

Leads Discovery and Optimization Bristol‐Myers Squibb Hopewell New Jersey USA

Yougan Cheng

Quantitative Clinical Pharmacology Bristol‐Myers Squibb Princeton New Jersey USA

Daniel J. Tenney

Leads Discovery and Optimization Bristol‐Myers Squibb Hopewell New Jersey USA

Tarek A. Leil

Quantitative Clinical Pharmacology Bristol‐Myers Squibb Princeton New Jersey USA