Aggregation-induced emission luminogens for image-guided surgery in non-human primates

Danni Zhong; Weiyu Chen; Zhiming Xia; Rong Hu; Yuchen Qi; Bo Zhou; Wanlin Li; Jian He; Zhiming Wang; Zujin Zhao; Dan Ding; Mei Tian; Ben Zhong Tang; Min Zhou

doi:10.1038/s41467-021-26417-2

Nature Communications (Nov 2021)

Aggregation-induced emission luminogens for image-guided surgery in non-human primates

Danni Zhong,
Weiyu Chen,
Zhiming Xia,
Rong Hu,
Yuchen Qi,
Bo Zhou,
Wanlin Li,
Jian He,
Zhiming Wang,
Zujin Zhao,
Dan Ding,
Mei Tian,
Ben Zhong Tang,
Min Zhou

Affiliations

Danni Zhong: Eye Center, the Second Affiliated Hospital, Zhejiang University School of Medicine
Weiyu Chen: The Fourth Affiliated Hospital, Zhejiang University School of Medicine
Zhiming Xia: Department of Nuclear Medicine, Shandong Provincial Hospital Affiliated to Shandong First Medical University
Rong Hu: NSFC Center for Luminescence from Molecular Aggregates, SCUT-HKUST Joint Research Institute, State Key Laboratory of Luminescent Materials and Devices, South China University of Technology
Yuchen Qi: Institute of Translational Medicine, Zhejiang University
Bo Zhou: Institute of Translational Medicine, Zhejiang University
Wanlin Li: Institute of Translational Medicine, Zhejiang University
Jian He: Institute of Translational Medicine, Zhejiang University
Zhiming Wang: NSFC Center for Luminescence from Molecular Aggregates, SCUT-HKUST Joint Research Institute, State Key Laboratory of Luminescent Materials and Devices, South China University of Technology
Zujin Zhao: NSFC Center for Luminescence from Molecular Aggregates, SCUT-HKUST Joint Research Institute, State Key Laboratory of Luminescent Materials and Devices, South China University of Technology
Dan Ding: Key Laboratory of Bioactive Materials, Ministry of Education, and College of Life Sciences, Nankai University
Mei Tian: Department of Nuclear Medicine, the Second Affiliated Hospital, Zhejiang University School of Medicine
Ben Zhong Tang: NSFC Center for Luminescence from Molecular Aggregates, SCUT-HKUST Joint Research Institute, State Key Laboratory of Luminescent Materials and Devices, South China University of Technology
Min Zhou: Eye Center, the Second Affiliated Hospital, Zhejiang University School of Medicine

DOI: https://doi.org/10.1038/s41467-021-26417-2
Journal volume & issue: Vol. 12, no. 1
pp. 1 – 13

Abstract

Read online

Most applications of aggregation-induced emission luminogens (AIEgens) have been limited in small animal models. Here, the authors show the versatility of AIEgens-based imaging-guided surgical operation from small animals to rhesus macaque, in support of the clinical translation of AIEgens.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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