Latent Autoimmune Diabetes in Adults and Metabolic Syndrome—A Mini Review

Niansi Pan; Shimei Yang; Xiaohong Niu

doi:10.3389/fendo.2022.913373

Frontiers in Endocrinology (Jun 2022)

Latent Autoimmune Diabetes in Adults and Metabolic Syndrome—A Mini Review

Niansi Pan,
Shimei Yang,
Xiaohong Niu

Affiliations

Niansi Pan: Department of Endocrinology, Changzhi Medical College, Changzhi, China
Shimei Yang: Department of Endocrinology, Changzhi Medical College, Changzhi, China
Xiaohong Niu: Department of Endocrinology, Changzhi Medical College Affiliated Heji Hospital, Changzhi, China

DOI: https://doi.org/10.3389/fendo.2022.913373
Journal volume & issue: Vol. 13

Abstract

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Latent autoimmune diabetes in adults (LADA) is a heterogeneous subtype of diabetes characterized by islet cell destruction mediated by islet autoimmunity and insulin resistance. Metabolic syndrome (MetS) is a state in which many risk factors for metabolic and cardiovascular diseases accumulate in an individual. Based on clinical data, this review covers the prevalence of MetS in LADA, focusing on the risk associated with and the role of insulin resistance in the development of LADA from the perspective of inflammatory factors, environmental factors, and the gut microbiota, aiming to improve our understanding of this condition.

Published in Frontiers in Endocrinology

ISSN: 1664-2392 (Online)
Publisher: Frontiers Media S.A.
Country of publisher: Switzerland
LCC subjects: Medicine: Internal medicine: Specialties of internal medicine: Diseases of the endocrine glands. Clinical endocrinology
Website: https://www.frontiersin.org/journals/endocrinology

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Abstract

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