Frontiers in Public Health (Aug 2021)

Case Report: Tropheryma whipplei Hide in an AIDS Patient With Pneumocystis Pneumonia

  • Jun Yan,
  • Binhai Zhang,
  • Zhongdong Zhang,
  • Jinchuan Shi,
  • Shourong Liu,
  • Jianjiang Qi,
  • Mengyan Wang

DOI
https://doi.org/10.3389/fpubh.2021.663093
Journal volume & issue
Vol. 9

Abstract

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Introduction:Pneumocystis pneumonia (PCP) is one of the most common opportunistic infections in HIV-infected patients. However, coinfection with Tropheryma whipplei is infrequent in AIDS patients with PCP.Case Presentation: We report a 28-year-old male AIDS patient coinfected with T. whipplei and Pneumocystis jirovecii diagnosed in the bronchoalveolar lavage. After sulfamethoxazole–trimethoprim and meropenem treatment, the patient showed clinical improvement in 2 weeks.Conclusion: Clinicians need to be alert to the occurrence of T. whipplei infection in AIDS patients with PCP and timely diagnosis and antibacterial treatments are essential. This case may help clinicians for timely diagnosis of the coinfection of T. whipplei and P. jirovecii in AIDS patients.

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