Медицинская иммунология (Jul 2014)

PSYCHOPHYSIOLOGICAL AND IMMUNE STATUS IN THE PATIENTS WITH RHEUMATOID ARTHRITIS

  • T. Y. Abramova,
  • I. G. Solov'eva,
  • A. E. Sizikov,
  • O. A. Gerzog,
  • A. E. Sulut'jan,
  • L. P. Konenkova,
  • I. V. Shishkova,
  • S. V. Abramov,
  • V. S. Kozhevnikov,
  • V. V. Abramov

DOI
https://doi.org/10.15789/1563-0625-2008-1-43-50
Journal volume & issue
Vol. 10, no. 1
pp. 43 – 50

Abstract

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Abstract. The aim of this study was to elucidate a role of brain hemispheres in formation of rheumatoid arthritis (RA). The parameters of higher nervous activity, autonomous and immune systems in these patients that were characterized by domination of the left or right hemispheres of a brain, were defined in present work. The results of this work allow of justifying the following items: a) relative increase in functional activity of right brain hemisphere in woman may represent a factor that either contributes to triggering of rheumatoid arthritis, or predisposes for its development; b) formation of rheumatoid arthritis in females is accompanied by complex changes in psychophysiological and immune parameters, that exhibit significant features depending on functional asymmetry of the hemispheres; c) a pronounced dependence is revealed between clinical course of disease and functional asymmetry of hemispheres.

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