Clinical and Translational Medicine (Feb 2023)
Selective degradation of the p53‐R175H oncogenic hotspot mutant by an RNA aptamer‐based PROTAC
- Lingping Kong,
- Fanlu Meng,
- Sijin Wu,
- Ping Zhou,
- Ruixin Ge,
- Min Liu,
- Linlin Zhang,
- Jun Zhou,
- Diansheng Zhong,
- Songbo Xie
Affiliations
- Lingping Kong
- Department of Medical Oncology Tianjin Medical University General Hospital Tianjin China
- Fanlu Meng
- Department of Medical Oncology Tianjin Medical University General Hospital Tianjin China
- Sijin Wu
- Laboratory of Molecular Modeling and Design State Key Laboratory of Molecular Reaction Dynamics Dalian Institute of Chemical Physics Chinese Academy of Sciences Dalian China
- Ping Zhou
- Center for Cell Structure and Function Shandong Provincial Key Laboratory of Animal Resistance Biology Collaborative Innovation Center of Cell Biology in Universities of Shandong College of Life Sciences Shandong Normal University Jinan China
- Ruixin Ge
- Center for Cell Structure and Function Shandong Provincial Key Laboratory of Animal Resistance Biology Collaborative Innovation Center of Cell Biology in Universities of Shandong College of Life Sciences Shandong Normal University Jinan China
- Min Liu
- Center for Cell Structure and Function Shandong Provincial Key Laboratory of Animal Resistance Biology Collaborative Innovation Center of Cell Biology in Universities of Shandong College of Life Sciences Shandong Normal University Jinan China
- Linlin Zhang
- Department of Medical Oncology Tianjin Medical University General Hospital Tianjin China
- Jun Zhou
- Center for Cell Structure and Function Shandong Provincial Key Laboratory of Animal Resistance Biology Collaborative Innovation Center of Cell Biology in Universities of Shandong College of Life Sciences Shandong Normal University Jinan China
- Diansheng Zhong
- Department of Medical Oncology Tianjin Medical University General Hospital Tianjin China
- Songbo Xie
- Center for Cell Structure and Function Shandong Provincial Key Laboratory of Animal Resistance Biology Collaborative Innovation Center of Cell Biology in Universities of Shandong College of Life Sciences Shandong Normal University Jinan China
- DOI
- https://doi.org/10.1002/ctm2.1191
- Journal volume & issue
-
Vol. 13,
no. 2
pp. n/a – n/a
Abstract
No abstracts available.
