INFECTION OF HUMAN HERPES VIRUS TYPE 6 IN CHILDREN WITH PYELONEPHRITIS

Abstract

The authors studied the incidence of detection of human herpes virus type 6 (HHV 6) infection markers in 207 children aged from 1 year to 7 years (126 children with acute pyelonephritis and 81 child in the control group with no signs of urinary tract infection). It was found out that of all the children studied ≥ 89,2% of the patients with acute pyelonephritis and ≥ 65,3% of the children without urinary tract infection are infected with HHV 6. The characteristic of HHV — 6 infection in children with acute pyelonephritis is the presence of active viral replication with the presence of HHV 6 DNA in the blood. This fact indicates the risk of repeated episodes of the disease and is the condition for administration of antiviral and / or immunotropic therapy. The authors proved low predictive value of HHV 6 DNA detection in urine of children with acute pyelonephritis.

Keywords

• children
• acute pyelonephritis
• 6 hhv infection