Sensors (May 2024)

Parkinson’s Kinetigraph for Wearable Sensor Detection of Clinically Unrecognized Early-Morning Akinesia in Parkinson’s Disease: A Case Report-Based Observation

  • Karolina Poplawska-Domaszewicz,
  • Naomi Limbachiya,
  • Yue Hui Lau,
  • Kallol Ray Chaudhuri

DOI
https://doi.org/10.3390/s24103045
Journal volume & issue
Vol. 24, no. 10
p. 3045

Abstract

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Early-morning off periods, causing early-morning akinesia, can lead to significant motor and nonmotor morbidity in levodopa-treated fluctuating Parkinson’s disease (PD) cases. Despite validated bedside scales in clinical practice, such early-morning off periods may remain undetected unless specific wearable technologies, such as the Parkinson’s KinetiGraph™ (PKG) watch, are used. We report five PD cases for whom the PKG detected early-morning off periods that were initially clinically undetected and as such, untreated. These five cases serve as exemplars of this clinical gap in care. Post-PKG assessment, clinicians were alerted and targeted therapies helped abolish the early-morning off periods.

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