Animals (Oct 2024)

Mitochondria-Targeted Antioxidant MitoQ Improves In Vitro Maturation and Subsequent Embryonic Development from Culled Cows

  • Zhihao Feng,
  • Junsong Shi,
  • Jiajie Ren,
  • Lvhua Luo,
  • Dewu Liu,
  • Yongqing Guo,
  • Baoli Sun,
  • Guangbin Liu,
  • Ming Deng,
  • Yaokun Li

DOI
https://doi.org/10.3390/ani14202929
Journal volume & issue
Vol. 14, no. 20
p. 2929

Abstract

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The purpose of this study was to investigate the effects and mechanisms of MitoQ on the IVM of culled bovine oocytes and subsequent embryonic development. The results revealed that in comparison to the control group (0 µmol/L), the IVM rate (p p p p p p < 0.05). In conclusion, MitoQ improved mitochondrial dysfunction, increased mitochondrial activity during IVM, and reduced oxidative stress, resulting in increased IVM rates and subsequent embryonic development from culled cows.

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