Plants (May 2021)

<i>Hibiscus sabdariffa</i>, a Treatment for Uncontrolled Hypertension. Pilot Comparative Intervention

  • Marwah Al-Anbaki,
  • Anne-Laure Cavin,
  • Renata Campos Nogueira,
  • Jaafar Taslimi,
  • Hayder Ali,
  • Mohammed Najem,
  • Mustafa Shukur Mahmood,
  • Ibrahim Abdullah Khaleel,
  • Abdulqader Saad Mohammed,
  • Hasan Ramadhan Hasan,
  • Laurence Marcourt,
  • Fabien Félix,
  • Nicolas Vinh Tri Low-Der’s,
  • Emerson Ferreira Queiroz,
  • Jean-Luc Wolfender,
  • Marie Watissée,
  • Bertrand Graz

DOI
https://doi.org/10.3390/plants10051018
Journal volume & issue
Vol. 10, no. 5
p. 1018

Abstract

Read online

In Iraq, in 2019, there were about 1.4 million Internally Displaced Persons (IDP); medical treatments were often interrupted. The feasibility of using Hibiscus sabdariffa (HS) decoction to curb hypertension was evaluated. A multicentric comparative pilot intervention for 121 participants with high blood pressure (BP) (≥140/90 mmHg) was conducted. Participants of the intervention group (with or without conventional medication) received HS decoction on a dose regimen starting from 10 grams per day. BP was measured five times over six weeks. The major active substances were chemically quantified. Results: After 6 weeks, 61.8% of participants from the intervention group (n = 76) reached the target BP n = 45). In the intervention group, a mean (±SD) reduction of 23.1 (±11.8) mmHg and 12.0 (±11.2) for systolic and diastolic BP, respectively, was observed, while in the control group the reduction was 4.4 (±10.2)/3.6 (±8.7). The chemical analysis of the starting dose indicated a content of 36 mg of total anthocyanins and 2.13 g of hibiscus acid. The study shows the feasibility of using HS decoction in IDP’s problematic framework, as hibiscus is a safe, local, affordable, and culturally accepted food product.

Keywords