PLoS ONE (Jan 2021)

Diagnosis of retinal disorders from Optical Coherence Tomography images using CNN.

  • Nithya Rajagopalan,
  • Venkateswaran N,
  • Alex Noel Josephraj,
  • Srithaladevi E

DOI
https://doi.org/10.1371/journal.pone.0254180
Journal volume & issue
Vol. 16, no. 7
p. e0254180

Abstract

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An efficient automatic decision support system for detection of retinal disorders is important and is the need of the hour. Optical Coherence Tomography (OCT) is the current imaging modality for the early detection of retinal disorders non-invasively. In this work, a Convolution Neural Network (CNN) model is proposed to classify three types of retinal disorders namely: Choroidal neovascularization (CNV), Drusen macular degeneration (DMD) and Diabetic macular edema (DME). The hyperparameters of the model like batch size, number of epochs, dropout rate, and the type of optimizer are tuned using random search optimization method for better performance to classify different retinal disorders. The proposed architecture provides an accuracy of 97.01%, sensitivity of 93.43%, and 98.07% specificity and it outperformed other existing models, when compared. The proposed model can be used for the large-scale screening of retinal disorders effectively.