Molecules (Dec 2009)

Synthesis and Antimicrobial Activity of Some Pyridinium Salts

  • Hüseyin Taşlı,
  • Ercin Erciyas,
  • Vildan Alptüzün,
  • Sülünay Parlar

DOI
https://doi.org/10.3390/molecules14125203
Journal volume & issue
Vol. 14, no. 12
pp. 5203 – 5215

Abstract

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Some substituted benzylidenehydrazinylpyridinium derivatives bearing benzyl, ethylphenyl and propylphenyl groups on the pyridinium nitrogen were synthesized and screened for possible antibacterial and antifungal activities against Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa and Candida albicans using the microdilution method. Antimicrobial test results indicated that compounds containing a 3-phenylpropyl chain displayed the highest antimicrobial activity against Staphylococcus aureus and the compound 3d was the most active in the series against all tested bacteria and fungi strains.

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