A case of severe hypothyroidism due to lenalidomide

Abstract

Abstract Lenalidomide, an immunomodulatory drug often used to treat multiple myeloma, can cause hypo‐ or hyperthyroidism. We present a patient being treated with lenalidomide for 2 years who developed severe hypothyroidism that was complicated by rhabdomyolysis and acute kidney injury. Thyroid function tests should be serially monitored in patients taking lenalidomide.

Keywords

• endocrinology
• hypothyroidism
• lenalidomide
• multiple myeloma (Neoplasia‐ myeloma and other plasma cell dyscrasias)
• rhabdomyolysis