Frontiers in Oncology (Jan 2024)

Renal venous sampling assisted the diagnosis of juxtaglomerular cell tumor: a case report and literature review

  • Di-en Yan,
  • Di-en Yan,
  • Hong-bing He,
  • Jian-ping Guo,
  • Yu-lan Wang,
  • Dan-ping Peng,
  • Huan-huan Zheng,
  • Xiao-zi Zhou,
  • Jin-xiang Fu,
  • Mei-li Wang,
  • Xian Luo,
  • Yun-feng Shen

DOI
https://doi.org/10.3389/fonc.2023.1298684
Journal volume & issue
Vol. 13

Abstract

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Juxtaglomerular cell tumor (JCT) is an endocrine tumor marked by elevated renin levels and high blood pressure. This case report presents the clinical findings of a 47-year-old woman with a history of recurrent hypokalemia, headaches, hypertension, and increased plasma renin activity (PRA). Dynamic enhanced magnetic resonance imaging (MRI) revealed a small nodule on the upper part of the right kidney. Selective renal venous sampling indicated a higher PRA only in the right upper pole renal vein. The patient underwent surgical removal of the right kidney mass, and the pathology results confirmed the diagnosis of JCT. This case underscores the importance of conducting selective renal venous sampling for accurate JCT diagnosis.

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