Clinical, Cosmetic and Investigational Dermatology (Jul 2023)
Generalized Vitiligo After Stem Cell Transplantation: A Case Report
Abstract
Yunxia Wang,1– 3 Wenting Hu,2 Fuquan Lin,2,3 Ai′e Xu2 1Department of Dermatology, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui Province, People’s Republic of China; 2Department of Dermatology, Hangzhou Third People’s Hospital, Hangzhou, Zhejiang Province, People’s Republic of China; 3Department of Dermatology, Hangzhou Clinical College of Anhui Medical University, Hangzhou, Zhejiang Province, People’s Republic of ChinaCorrespondence: Ai′e Xu, Hangzhou Third People’s Hospital, No. 38 Xihu Avenue, Shangcheng District, Hangzhou, Zhejiang Province, People’s Republic of China, Tel +86-131 5513 0536, Fax +86+ 571+87827534, Email [email protected]: Graft versus host disease (GVHD) is a complex immune-mediated pathophysiological process, which is caused by allogenic immune reactions between donors and recipients. No matter ac-ute or chronic GVHD, skin involvement is the most common, severe skin damage can lead to permanent disfigurement, which seriously affects the long-term quality of life of patients. We herein report a patient with generalized vitiligo after allogeneic peripheral hematopoietic stem cell transplantation (allo-HSCT) for aplastic anemia.Keywords: graft versus host disease, vitiligo, aplastic anemia, allogeneic peripheral hematopoietic stem cell transplantation
