Frontiers in Nuclear Engineering (Oct 2023)
Dosimetry for boron neutron capture therapy developed and verified at the accelerator based neutron source VITA
- Marina Bikchurina,
- Timofey Bykov,
- Ibrahim Ibrahim,
- Ibrahim Ibrahim,
- Ibrahim Ibrahim,
- Anna Kasatova,
- Dmitrii Kasatov,
- Iaroslav Kolesnikov,
- Victoria Konovalova,
- Victoria Konovalova,
- Timur Kormushakov,
- Timur Kormushakov,
- Alexey Koshkarev,
- Alexey Koshkarev,
- Anton Kuznetsov,
- Anton Kuznetsov,
- Vyacheslav Porosev,
- Sergey Savinov,
- Ivan Shchudlo,
- Nataliia Singatulina,
- Nataliia Singatulina,
- Evgeniia Sokolova,
- Tatiana Sycheva,
- Iuliia Taskaeva,
- Gleb Verkhovod,
- Sergey Taskaev,
- Sergey Taskaev
Affiliations
- Marina Bikchurina
- Budker Institute of Nuclear Physics, Novosibirsk, Russia
- Timofey Bykov
- Budker Institute of Nuclear Physics, Novosibirsk, Russia
- Ibrahim Ibrahim
- Budker Institute of Nuclear Physics, Novosibirsk, Russia
- Ibrahim Ibrahim
- Novosibirsk State University, Novosibirsk, Russia
- Ibrahim Ibrahim
- Tartous University, Tartous, Syria
- Anna Kasatova
- Budker Institute of Nuclear Physics, Novosibirsk, Russia
- Dmitrii Kasatov
- Budker Institute of Nuclear Physics, Novosibirsk, Russia
- Iaroslav Kolesnikov
- Budker Institute of Nuclear Physics, Novosibirsk, Russia
- Victoria Konovalova
- Budker Institute of Nuclear Physics, Novosibirsk, Russia
- Victoria Konovalova
- Novosibirsk State University, Novosibirsk, Russia
- Timur Kormushakov
- Budker Institute of Nuclear Physics, Novosibirsk, Russia
- Timur Kormushakov
- Novosibirsk State University, Novosibirsk, Russia
- Alexey Koshkarev
- Budker Institute of Nuclear Physics, Novosibirsk, Russia
- Alexey Koshkarev
- Novosibirsk State University, Novosibirsk, Russia
- Anton Kuznetsov
- Budker Institute of Nuclear Physics, Novosibirsk, Russia
- Anton Kuznetsov
- Novosibirsk State University, Novosibirsk, Russia
- Vyacheslav Porosev
- Budker Institute of Nuclear Physics, Novosibirsk, Russia
- Sergey Savinov
- Budker Institute of Nuclear Physics, Novosibirsk, Russia
- Ivan Shchudlo
- Budker Institute of Nuclear Physics, Novosibirsk, Russia
- Nataliia Singatulina
- Budker Institute of Nuclear Physics, Novosibirsk, Russia
- Nataliia Singatulina
- Novosibirsk State Technical University, Novosibirsk, Russia
- Evgeniia Sokolova
- Budker Institute of Nuclear Physics, Novosibirsk, Russia
- Tatiana Sycheva
- Budker Institute of Nuclear Physics, Novosibirsk, Russia
- Iuliia Taskaeva
- Budker Institute of Nuclear Physics, Novosibirsk, Russia
- Gleb Verkhovod
- Budker Institute of Nuclear Physics, Novosibirsk, Russia
- Sergey Taskaev
- Budker Institute of Nuclear Physics, Novosibirsk, Russia
- Sergey Taskaev
- Novosibirsk State University, Novosibirsk, Russia
- DOI
- https://doi.org/10.3389/fnuen.2023.1266562
- Journal volume & issue
-
Vol. 2
Abstract
The method of boron neutron capture therapy for malignant tumors, proposed in 1936, is beginning to enter clinical practice. The development of dosimetry tools for characterization of therapeutic mixed neutron-photon beam and assessing the patient’s response to treatment is becoming relevant. In this work, a number of dosimetric techniques have been developed: a compact neutron detector with a pair of cast scintillators, one of which is enriched with boron, to measure the boron dose and the γ-ray dose; cell dosimeter for measuring the sum of the equivalent dose of fast neutrons and the equivalent nitrogen dose; prompt γ-ray spectroscopy for in situ measurement of boron dose in real time; epithermal neutron flux monitor for measuring the epithermal neutron flux. Their verification carried out on the accelerator based neutron source VITA showed that they can become convenient and reliable tools for characterization of neutron beam and assessing the patient’s response to treatment.
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