Guoji Yanke Zazhi (Dec 2020)

Research status of virus-related corneal endotheliitis

  • Yan-Ling Li,
  • Wang-Ming Su,
  • Xiao-Hui He

DOI
https://doi.org/10.3980/j.issn.1672-5123.2020.12.12
Journal volume & issue
Vol. 20, no. 12
pp. 2074 – 2078

Abstract

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The virus-related corneal endotheliitis has diverse inducement, complex etiology, unclear pathogenesis, diverse clinical manifestations. There is no unified classification at present. Auxiliary diagnosis technology is improving constantly, loop-mediated isothermal amplification and all kinds of PCR have a certain auxiliary role in the diagnosis of this disease. But the diagnosis also mainly relys on history and clinical manifestation in clinic. Anti-viral drug and glucocorticoid are the main treatment. Virus-related corneal endotheliitis has high recurrence rate, so there is an urgent need to research new drugs and new treatment. Experiment researches of genetic engineering drugs, such as vaccines, unwinding-primers enzyme inhibitors, and chemokine receptors, bring hope to the treatment of virus-related corneal endotheliitis. The purpose of this article is to review the related research of virus-related corneal endotheliitis.

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