Disruption of KDM4C-ALDH1A3 feed-forward loop inhibits stemness, tumorigenesis and chemoresistance of gastric cancer stem cells

• Tingyuan Lang,
• Jia Xu,
• Lei Zhou,
• Zhiqi Zhang,
• Xinli Ma,
• Jiayi Gu,
• Jingshu Liu,
• Yunzhe Li,
• Dongyan Ding,
• Jiangfeng Qiu

Affiliations

Tingyuan Lang

Department of Gynecologic Oncology, Chongqing University Cancer Hospital, School of Medicine, Chongqing University

Jia Xu

Department of Gastrointestinal Surgery, Renji Hospital Shanghai Jiao Tong University School of Medicine

Lei Zhou

Singapore Eye Research Institute, The Academia

Zhiqi Zhang

Department of General Surgery, Shanghai Fourth People’s Hospital Affiliated to Tongji University School of Medicine

Xinli Ma

Department of Gastrointestinal Surgery, Renji Hospital Shanghai Jiao Tong University School of Medicine

Jiayi Gu

Department of Gastrointestinal Surgery, Renji Hospital Shanghai Jiao Tong University School of Medicine

Jingshu Liu

Department of Gynecologic Oncology, Chongqing University Cancer Hospital, School of Medicine, Chongqing University

Yunzhe Li

Department of Gynecologic Oncology, Chongqing University Cancer Hospital, School of Medicine, Chongqing University

Dongyan Ding

Department of Gynecologic Oncology, Chongqing University Cancer Hospital, School of Medicine, Chongqing University

Jiangfeng Qiu

Department of Gastrointestinal Surgery, Renji Hospital Shanghai Jiao Tong University School of Medicine