Mustafa Kemal Üniversitesi Tıp Dergisi (Mar 2015)

İSOTRETİNOİN TEDAVİSİNİN NÖTROFİL/LENFOSİT ORANI VE DİĞER HEMOGRAM PARAMETRELERİNE ETKİSİNİN DEĞERLENDİRİLMESİ

  • Pınar Özuğuz,
  • Seval Kaçar,
  • Serap Polat,
  • Sena Ulu,
  • Şemsettin Karaca

DOI
https://doi.org/10.17944/mkutfd.56798
Journal volume & issue
Vol. 4, no. 13
pp. 9 – 14

Abstract

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Aim: There are reports of various side effects of isotretinoin. Recent studies have controversial results about the necessity of laboratory investigation including hemogram and blood chemistry of patients during the follow up periodon isotretinoin.We aimed to investigate the effects of isotretinoin on Neutrophil/lymhocyte ratio (NLR) a systemic inflammation marker and the other hemogram parameters. Material and methods: Sixty seven patients with moderate to severe acne vulgaris aged between 18 to 25, who were prescribed 0.5mg/kg isotretinoin, were included to the study. Patients’ hemogram parameters before treatment and at the third month of treatment were recorded on SPSS 20.0 programme retrospectively. The difference between two values

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