Surgical tactics for esophageal cancer with complete pathomorphosis after chemoradiotherapy

Abstract

Esophageal cancer is an oncological disease with a poor prognosis due to late diagnosis and detection of the tumor at a late stage. At present, the combined method of treatment is generally accepted for this pathology, starting from stage IIA. Preoperative chemoradiation therapy in this approach helps to achieve not only partial but also complete regression of the tumor. The question of the necessity of surgical tactics in this group of patients, due to the lack of clear recommendations, remains controversial at present. The article presents a successful case of neoadjuvant chemoradiation therapy, which made it possible to achieve not only clinical, but also complete pathomorphological regression of the tumor. This tumor response to chemoradiation therapy occurs in less than a third of all patients with esophageal cancer. Despite this, complete regression of the tumor does not mean recovery.

Keywords

• esophageal cancer
• locally advanced esophageal cancer
• combined treatment of esophageal cancer
• complete tumor pathomorphosis
• clinical case